Abstract
In this work, the multi-frequency impedance both in normal and liver cancer tissues was studied. This was to investigate the feasibility to detect liver cancer by a low cost, easy to use, and a relatively non-invasive electrical impedance measure technique, and thus potentially improving liver cancer diagnosis. Hepatocellular carcinoma (HCC) was induced in male Wistar rats by the administration of diethylnitrosamine (DEN) during 16weeks. The electrical impedances at a frequency sweep of 10-100KHz in the whole body and 10-60KHz in the liver were taken at the end of the treatment. The electrical impedance showed that the real component values of the impedance change in HCC. In addition, we found that the imaginary component was not associated with HCC. Our results suggest that the electrical impedance may be used as a diagnostic HCC tool.
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