Abstract

Effects of hypertension, aldosterone, and/or mineralocorticoid receptor activation on inflammatory and fibrotic effects in the vasculature of the heart, kidney, and brain in patients with treatment-resistant hypertension. Abbreviations: Ang I, angiotensin I; Ang II, angiotensin II; CCBs, calcium channel blockers; ACEIs, angiotensin-converting enzyme inhibitors; ARBs, angiotensin receptor blockers; TT, thiazide-type (indapamide and chlorthalidone); MRAs, mineralocorticoid receptor antagonists.

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