Resistance to diet-induced obesity conferred by dietary bile acid supplementation in mice is strain specific

Abstract

Bile acids (BA) may function as signaling molecules in a number of peripheral target tissues. It has already been shown that BA confer resistance to diet-induced obesity (DIO) in brown adipose tissue of C57BL/6J (B6) mice by inducing thermogenesis. In our study, we aimed to assess the relevance of brown adipocytes within white adipose tissue depots in this context.