Resistance to antimicrobial preparations of Enterococcus isolated from milk during infectious mastitis in cows

Abstract

For successful pharmacotherapy of animals, it is important to identify species of Enterococcus faecalis pathogens isolated from milk in infectious mastitis of cows, analyze the antibiogram and interpret the results, and laboratory control over the mechanisms of antibiotic resistance. This is necessary for veterinarians to rationally select antibacterial drugs and predict their clinical effectiveness. The purpose of the study was to study the resistance to antimicrobial drugs of Enterococcus faecalis bacteria isolated from milk in infectious mastitis of cows. In the period from 2021 to 2022, 100 strains of microorganisms were isolated from the mastitis milk of cows. The obtained strains were identified as gram-negative bacteria in 32% of isolation cases, gram-positive bacteria - 68%, of which 14% were Enterococcus faecalis. When interpreting the antibiogram, most isolates of Enterococcus faecalis are sensitive to tetracycline in 21.4% of isolation cases, ampicillin, amoxicillin in 100%. It was noted resistant to tetracycline in 78.6% of cases of isolation, gentamicin, cephalexin, cefotaxime, erythromycin, clindamycin, lincomycin, tobramycin, ceftriaxone and streptomycin in 100%. Antibiotic resistance correlates with the clinical failure of antimicrobials in veterinary medicine. Multi-resistance of Enterococcus faecalis to various groups of antibacterial agents leads to limited use of antibiotics, which significantly reduces the possibilities of therapy and affects the economic condition of agriculture.