Resistance profile to antimicrobials and antimicrobial activity of the aqueous extract of Pereskia aculeata Mill. in enterobacteria isolated at different stages of broiler chicken raising

Abstract

The emergence of resistant enterobacteria is common in poultry farming, increasing the search for alternatives. The objective was to evaluate the antimicrobial resistance profile, the presence of strains producing extended spectrum beta-lactamase (ESBL) and the Minimum Inhibitory Concentration (MIC) of Pereskia aculeata Mill. extract against enterobacteria isolated from a poultry industry. 100 samples were collected, involving broiler breeders, eggs, chicks and broiler chickens from two origins (breeders). Antimicrobial susceptibility was assessed using the disk diffusion and synergistic double-disk tests for ESBL. The MIC of the P. aculeata extract was performed using the broth microdilution method. No differences (P>0.05) were found in the resistance profile of the isolates in relation to the origin, however, greater resistance was detected for quinolones and beta-lactams. The MIC of P. aculeata extract determined in eight isolates obtained from a broiler chicken production chain was 12 mg/mL, considered high, demonstrating the need for studies that search for new alternative bioactives.