Abstract
Antimicrobial resistance among Enterobacteriaceae is unavoidable in modern medicine, and it is a major concern in the treatment of bacterial infections both in the hospital and in the community. Extended spectrum β-lactamases (ESBL) are enzymes produced by a range of Gram negative bacteria that provide greater antibiotic resistance. This article aims to determine the antimicrobial resistance pattern of re-emerging ESBL producing Enterobacteriaceae isolated from diarrhea patients in Enugu. Its objective is to isolate ESBL producing bacteria, investigate the prevalence of ESBL producing bacteria in patients and determine antimicrobial sensitivity profile. Clinical stool samples were collected from diarrhea patients from two hospitals in Enugu and were isolated on Cysteine Lactose Electrolyte Deficient (CLED) and Salmonella Shigella agar, a total of 35 isolates were obtained from which only 9 isolates were identified as potential Esbl producing organisms after phenotypical method and double disk synergy.
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