Abstract

Summary1. Human respiratory tract mucin possesses a resistance lowering factor similar in activity to that of hog gastric mucin. This effect was shown by intrabronchial inoculation of rats with pneumococci suspended in saline or the two types of mucin. It was also shown by intraperitoneal inoculation of mice with streptococci suspended in saline, in two types of mucin and in fractions thereof. 2. Evidence against resistance lowering properties of mucin depending on the presence of blood group A antigen was obtained by fractionating human respiratory tract mucin and testing the fractions for blood group A antigen and the resistance lowering properties of the fractions.

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