Abstract

Bacteria Escherichia coli (E.coli) is a ubiquitous microorganism with a different serotypes, that cause septicemia in neonatal piglets, diarrhea in suckling piglets, diarrhea and edemic disease in weaned piglets. Vaccination and antibiotic treatment are less effective ways in solving the problem, especially when the category of pig is not taken into consideration, as well as feed safety and chemical composition of feed. The resistance of pathogens depends on the farm size, production type and pigs category raised on the farm. In addition, the antibiotics used for veterinary purposes reduce their effectiveness in human medicine. Analyzing the antibiograms results obtained from the isolates of dead piglets with E. coli infection in last two years (2007-2009), it can be concluded that E. coli strains developed resistance to most chemotherapeutics. Applying bacteriological examination it was detected that the isolates of E. coli are highly sensitive to the following chemotherapeutics: Floron (86.36%), Cobactam (71%), Enrofloxacin (54.84%), Neomycin (38.71%), Gentamicin (38.71%), Lincospectin (29%), Flumequine (29%), Amoxicillin (26.66%), Colistin (17.39%), Penicillin (9.67%), Tiamulin (6.45%), Tetracycline (6.45%), Doxycycline (6.45%), Streptomycin (3.22%). Intermediate degree of sensitivity was found with: Flumequin (38.71%), Colistin (34.78%), Cobactam (30%), Tilozin (29.17%), Gentamicin (25%). E. coli strains were the least resistant to Cobactam (not detected), Floron (4.54%), Neomycin (12.9%), Colistin (13.04%), Flumequin (19.35%).

Highlights

  • Diarrhea in sucking and postweaning piglets causes economic losses due to mortality, morbidity, reduced daily gain, increased conversion and costs caused by treating sick piglets

  • From the organs of dead pigs showing the signs of E. coli infection, the appearance of resistance of E. coli strains to a number of chemotherapeutics was determined

  • Bacteriology examination showed that E. coli isolates were highly sensitive to these chemotherapeutics: floron (86.36%), cobactam (71%), enrofloxacin

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Summary

Introduction

Diarrhea in sucking and postweaning piglets causes economic losses due to mortality, morbidity, reduced daily gain, increased conversion and costs caused by treating sick piglets. It is usually caused by Escherichia coli infection bearing f4. Edema disease is caused by the strains that have f 18 and f18ac associated with diarrhea (Debroy et al, 2009). The extensive use of antibiotics in bacterial infections in human and veterinary medicine select for resistant microorganism which may, in turn, transfer resistance factor to other bacteria thereby further enhancing their spread (Levy, 1984; Levy, 1988). Because of the intensive use of antimicrobial agents in the production of feed, meat is frequently contaminated with resistant strains of E. coli.

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