Residual Cervical Thymus: A Normal CT Finding That May Be Present Throughout Patients' Lives.

Abstract

Although the thymus is centered in the mediastinum, often a cervical component can be seen in children and young adults. The frequency of radiologically evident residual cervical thymus in older adults is not known. The purpose of our study was to determine the proportion of adults who have residual cervical thymus visible on contrast-enhanced neck CT. We retrospectively identified 700 patients who had undergone contrast-enhanced CT between February 2013 and August 2013. We categorized the patients by decade of life and calculated the proportion in which residual cervical thymic tissue could be detected. The location of the tissue focus, greatest axial diameter, and distance above the manubrium were recorded. A multivariate model was used to determine whether age or sex predicted the likelihood of identifiable cervical thymus, the size of residual thymus, or the distance of residual thymus above the sternum. Of the 700 patients, 157 (22.4%) had residual cervical thymus. The mean distance of the residual thymus above the manubrium was 13.4 ± 7.26 mm. The mean size of the residual cervical thymus was 12.5 ± 4.11 mm. The frequency of residual thymus decreased exponentially with age. There was a statistically significant relationship between age and the size of the residual cervical thymus (P = .02). Most of the cervical thymic tissue was found in the left paratracheal region. Residual cervical thymus may be present at any age, though the frequency decreases with increasing age.