Abstract
This review discusses about biomimetic medical materials for tissue engineering of bone and cartilage, after previous scientific commentary of the invitation-based, Korea-China joint symposium on biomimetic medical materials, which was held in Seoul, Korea, from October 22 to 26, 2015. The contents of this review were evolved from the presentations of that symposium. Four topics of biomimetic medical materials were discussed from different research groups here: 1) 3D bioprinting medical materials, 2) nano/micro-technology, 3) surface modification of biomaterials for their interactions with cells and 4) clinical aspects of biomaterials for cartilage focusing on cells, scaffolds and cytokines.
Highlights
Scaffolds with bimimetics have been developed for tissue engineering, based on the sciences and engineering of biomaterials and nano/microstructures of defect tissues
Defect sizes, extracellular matrix (ECM) domains, biological molecules and ECM structures are typical examples of major components and properties of defect tissues, which require tissue regeneration. 3D bioprinting among many technologies in tissue engineering has been applied to fabrications of scaffolds based on understanding of tissue morphologies and physicochemical properties in nano/micro levels, even though 3D bioprinting has at current stages many huddles to be overcome to its clinical applications
Combination of 3D bioprinting and micro/nano-technology has been utilized in tissue engineering area, being considered as a unique technology to overcome the issues of fabrications of biomimetic scaffolds for complex tissues
Summary
Scaffolds with bimimetics have been developed for tissue engineering, based on the sciences and engineering of biomaterials and nano/microstructures of defect tissues. 3D bioprinting among many technologies in tissue engineering has been applied to fabrications of scaffolds based on understanding of tissue morphologies and physicochemical properties in nano/micro levels, even though 3D bioprinting has at current stages many huddles to be overcome to its clinical applications.
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