Abstract
With data from the UK Biobank (n=401 219; median follow-up 8·1 years) and 21 cohorts included in the Emerging Risk Factors Collaboration (ERFC; n=162 036; median follow-up 9·5 years), Eric Harshfield and colleagues investigated the association between depressive symptoms and cardiovascular disease (CVD). Results from the ERFC showed that for each 1-SD higher depression score, there was an increased risk of stroke (hazard ratio [HR] 1·05 [95% CI 1·01–1·10]), coronary heart disease (1·07 [1·03–1·11]), or a composite of the two outcomes (1·06 [1·04–1·08]).
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