Abstract
In a systematic review and meta-analysis of 15 prospective cohort studies (n=191 130), Matthew Pearce and colleagues examined the links between physical activity and depression. Results indicated that lower levels of physical activity were associated with increased risk of incident depression, with the authors noting that an inverse curvilinear dose–response association was present (I2=74%; p<0·001). Compared with adults who reported no physical activity, the relative risk of depression in individuals who did half the recommended activity volume was 0·82 (95% CI 0·77–0·87), and in those who did the recommended activity volume (eg, 2·5 h of brisk walking per week), it was reduced further to 0·75 (0·68–0·82). Increasing physical activity above recommended levels conferred modest additional benefits on depression.
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