Abstract

The incidence of ischemic stroke in the middle cerebral artery(MCA)territory is high.Despite intravenous thrombolytic therapy with recombinant tissue type plasminogen activator(rt-PA)can be used at the early stage, the patients seldom gain benefits from that, and the morbidity and mortality stay high.In order to provide evidence for optimizing early identification and clinical treatment of patients at high risk of ischemic stroke, this article reviewed the current state of science and technology regarding prognosis-influencing factors for ischemic stroke of the middle cerebral artery territory, such as stroke pathogenesis, the length and site of vessel occlusion, the collateral circulation and lesion patterns, initial symptoms and clinical intervention, and other related indexes after thrombolysis. Key words: Brain infarction; Middle cerebral artery; Thrombolytic therapy; Prognosis

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