Abstract

Fractalkine (Fkn) is the only member of CX3C subfamily of chemokine currently found, cx3cr1 is its specific receptor. Fkn/cx3cr1 is involved in inflammation, cancer, autoimmune diseases, allergy, acquired immune deficiency syndrome and other diseases, while its variety of pathophysiological role is accomplished by microglia. Functions of Fkn/cx3cr1 and microglia in age-related macular degeneration, acute light damage disease, retinal vascular disease, diabetic retinopathy disease, uveitis and other retina disease were reviewed in this article. Key words: Fractalkine; Cx3cr1; Microglia; Retina

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call