Abstract

Bronchial asthma (asthma) is a chronic inflammatory disorder of the airways,but its pathogenesis is incompletely understood.While asthma is a complex disease caused by multiple factors,airway epithelial barrier damage is a cardinal feature.We review the protective mechanism of airway epithelial barrier to asthma. Key words: Bronchial asthma; Airway surface liquid; Epithelial cell; Epidermal growth factor receptor; VIP ; Zinc ; Toll-like receptors; Tight junctions

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