Abstract

Organophosphate ester (OPEs) has been widely used as a substitute of brominated biphenyl ethers and other brominated flame retardant (BFRs), and their health effects and environmental impacts are widely concerned. This article systematically reviews the common types, metabolites, environmental occurrences, exposure pathways, levels, toxic effects and biomarkers of OPEs, in order to explore the relationships between OPEs exposures and biomarkers, to reveal the potential mechanisms of health effects, and to provide references and scientific basis for the health effects of OPEs exposure in China.

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