Abstract
The incidence of infertility is on rise in the past decade, and its etiology is complex and diverse, including female factors, male factors and both factors. Heat shock protein 70 (HSP70) is the most conservative and most characteristic of HSP family. It is involved in immune response, anti-apoptosis, molecular chaperone, protect cells from stress and other functions. Studies show that HSP70 is closely related to these diseases caused infertility. The article reviews the relationship between HSP70 and infertility. Key words: Heat shock protein 70 (HSP70); Infertility; Poly cystic ovary syndrone (PCOS); Endometriosis (EMS); Premature ovarian failure(POF); Male infertility; Recurrent spontaneous abortion (RSA)
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