Abstract
Epidermal growth factor receptor (EGFR) -tyrosine kinase inhibitors (TKI) have transformed traditional cancer treatment and brought good news to patients with non-small cell lung cancer. However, drug resistance problems arise one after another. Based on further exploration of the mechanism of EGFR resistance and corresponding therapeutic strategies, the author reviewed relevant literature, classified and summarized it, providing ideas for solving the clinical problem of EGFR resistance and providing hope for tumor patients.
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