Abstract
胰腺炎后糖尿病（PPDM）常于胰腺急性或慢性炎症后发生，这是一种典型的继发性糖尿病，其中急性胰腺炎后糖尿病（PPDM-A）是主要疾病之一。急性胰腺炎（AP）时胰腺局部炎症反应，严重损伤散布在胰腺组织中的胰岛α细胞、β细胞，使胰高血糖素分泌增加和胰岛素分泌减少，最终引起机体血糖升高。PPDM-A血糖控制差，使用胰岛素较早，胰腺导管腺癌发病率高，病死率高。识别危险因素对早期有效预防PPDM-A具有重要的临床意义，目前应激性高血糖，慢性持续低度炎症，脂质代谢障碍，胰腺细胞坏死和损伤被认为是PPDM-A的危险因素，因此本文围绕以上几个方面进行论述。.
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