Abstract
Azo bonds as reactive sites can be widely applied to many fields. Through the introduction of azo bonds, multiple functions can be commendably combined on the basis of the single function of the original system. Studies are focused on the photoisomerization properties and applications of azobenzene derivates. However, the reduction and cleavage reactions of azo bonds have attracted more and more attention in recent years because of their application in vivo . This review mainly introduced the mechanism and properties of reductants that include glutathione, sodium dithionite and azoreductase. The reductive cleavage properties of azobenzenes and their research progress in the biological field are described, and the future development prospects are also discussed.
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