Abstract

免疫检查点抑制剂(ICI)能阻断肿瘤的免疫逃逸机制,其临床适应证在不断扩展,极大地改善了多种晚期恶性肿瘤患者的临床预后,但免疫相关不良事件的报道也随之增加。心包疾病是最常见ICI相关心血管不良反应,起病隐匿,在急性期具有高致死率。该综述展示了近几年来ICI相关心包疾病的发病概况、致病机制、临床表现、监测和处理原则等方面的研究进展,以期提高临床医师对该疾病的认识和应对能力。.

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