Research progress on mechanical properties and wear resistance of cartilage repair hydrogel

Abstract

Hydrogel is a porous three-dimensional network material that is insoluble in water and can store a large amount of water. This material has excellent mechanical properties, such as medical fields, wastewater treatment and other fields, and are widely used. With the development of modern science and technology, the research on hydrogel, a new kind of biomaterial, is increasingly extensive. Many researchers have carried out research on bone tissue-related engineering based on the advantages of hydrogel, such as adjustable mechanical properties, convenient production and combination with bioactive factors. The researchers mainly focus on the mechanical properties and biocompatibility of hydrogel made of composite materials. The disease causes extensive trauma, broken bones and cartilage damage that does not heal on its own, while traditional surgical treatments can bring side effects such as infection, inflammation and pain. As a new kind of biomaterial, hydrogel has controllable mechanical properties and biocompatibility, and is widely used in bone tissue engineering as scaffold material for growth factor transport and cell adhesion. In order to make hydrogels more suitable for local treatment of orthopedic diseases, the excellent properties of hydrogels are combined with synthetic materials with advanced technologies in different fields. In this paper, the test methods used in the study of mechanical and tribological properties of bone repair hydrogels are reviewed, and the shortcomings of experimental methods in the study of cartilage repair hydrogels are pointed out. the application of the combination of mechanics and tribology in the study of cartilage repair and cartilage replacement was discussed, and the research progress of molecular dynamics in characterizing the micromechanical state of hydrogel was summarized.