Abstract
Liver transplantation has become the most effective treatment for end-stage liver diseases. Due to the shor-tage of organ, more and more extended criteria donors (ECD) grafts had been used, which expand the liver pool. However, a series of complications post transplantation were caused by ischemia, hypoxia, steatosis and so on. The non-anastomotic biliary strictures after liver transplantation is one of the major complications when the ECD donors was be used in clinic. The study on the protective effect of machine perfusion on liver donors is too numerous to list, and existing studies have found that MP can reduce the incidence of NAS after liver transplantation. This review provides an overview of the pathogenesis of NAS and the reduction incidence of NAS by MP. Key words: Live transplantation; Donor; Machine perfusion; Non-anastomotic biliary strictures; Complication
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