Research progress on inhibitors of epidermal growth factor receptor and its mutations in lung cancer treatment

Abstract

Epidermal growth factor receptor inhibitors are the research focus in the molecular targeted therapy of lung cancer. Epidermal growth factor receptor inhibitors have been widely used for the treatment of non-small cell lung cancer. In recent years, it has been found that epidermal growth factor receptor mutation and its inhibitors are closely related to the clinical efficacy. This article reviews the research progress of epidermal growth factor receptor inhibitors and its mutation in the therapy of lung cancer. Key words: Epidermal growth factor receptor; Gene mutation; Lung cancer