Research progress on effects of 3D-printed antler powder scaffolds on biological behavior of macrophages

Abstract

Macrophages are important cells in the regulation of host immune and inflammatory response. Host inflammatory response is the normal response of tissue to injury and foreign body. The intensity and persistence of inflammation affect the biocompatibility and stability of biomaterials in vivo. Therefore, its responsiveness to biomaterials plays an important role in the cognitive material-host response. The effect of scaffold material on the biological behavior of macrophages plays an important role in the process of bone tissue regeneration. Calcined deer horn cancellous bone is a new type of bone graft material. By studying the influence of deer horn powder /PVA scaffold material on the biological behavior of macrophages, the relationship between subtypes of macrophages and bone regeneration is understood, and the advantages of deer horn powder as a new bone graft material are understood.