Abstract

Plasminogen activator inhibitor-1 (PAI-1) is one of the members of the family of serine protease inhibitors,is fast,specific,effective physiological inhibitor of plasminogen activator,can affect process of fibrinolysis involved by tissue-type plasminogen activator,as well as fibrinolysis,extracellular matrix loops,cell migration,tissue repair,tumor invasion and metastasis process involved by urokinasetype plasminogen activator under physiological and pathological conditions. Key words: Plasminogen activator inhibitor-1; Pulmonary thromboembolism; Pulmonary fibrosis; Bronchial asthma

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