Abstract

Upconversion nanomaterials (UCNPs) have attracted much attention in recent years due to their unique advantages. Compared to the traditional luminescence materials, UCNPs could convert low energy near-infrared excitation light into ultraviolet and visible light, which have some advantages, such as strong tissue penetration, low cytotoxicity, and weak background fluorescence. Combined with high resolution CT and MRI, UCNPs make multimodality imaging and accurate treatment possible. This review summarizes the research progress of UCNPs in biological imaging and cancer therapy. Key words: Neoplasms; Nanoparticles; Diagnostic imaging; Phototherapy; Trends

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