Abstract

Pre-eclampsia (PE) is a common obstetric syndrome affecting about 9.4% of pregnant women in our country. The etiology and pathogenesis of PE are not fully understood. Some literatures found that the onset of PE was an imbalance of maternal-fetal immune tolerance. Maternal immune system can not recognize the fetal alloantigen and the activation of cell-mediated immunity which may play a role in the etiology of PE. PE has an immune imbalance of helper T cell (Th)1/Th2. Recent data suggest that PE is a Th17/regulatory T cell (Treg) immune imbalance with a predominance of Th17 immunity. The latest research progress about relationship between Th17/Treg immune imbalance and PE will be reviewed. Key words: Pre-eclampsia; Th17 cells; T-lymphocytes

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