Abstract

Metabolism is a necessary condition for cell survival and development. Reactive oxygen species arise from cell metabolism, while maintaining normal physiological activity of cells, reactive oxygen species can also cause normal cells to transform into tumor cells. Compared with normal cells, hepatocellular carcinoma cells produce and accumulate more reactive oxygen species during the metabolic process due to metabolic changes. These accumulated reactive oxygen species not only can promote the occurrence and development of hepatocellular carcinoma, but also can endanger the survival of it. This article summarizes the research of reactive oxygen species and hepatocellular carcinoma in recent years. Key words: Reactive oxygen species; Hepatocellular carcinoma; Mitochondria

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