Abstract
Anaplastic thyroid cancer is a rare and aggressive disease with a dismal prognosis and an overall survival measured in months.Nearly 50% of patients at diagnosis have locally advanced or distant metastases.Therefore, there is a lack of effective treatment.Recently, programmed cell death-1 (PD-1)/programmed cell death ligand-1(PD-L1), as a highly promising immune therapy, has shown good efficacy in a variety of tumors.This article aims to review biological effects, drug progression and research status of PD-1/PD-L1 in anaplastic thyroid cancer.It helps to provide some new ideas for the treatment of anaplastic thyroid cancer. Key words: Anaplastic thyroid cancer; Immune therapy; Programmed cell death-1/Programmed cell death ligand-1
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