Research progress of positron-emitting molecular imaging probes for Alzheimer′s disease

Abstract

As an advanced imaging technology, PET provides high sensitivity and accuracy for the diagnostic research of Alzheimer′s disease (AD). Various pathophysiological information of AD can be illustrated by applying different molecular imaging probes. Three series of molecular imaging probes including glucose metabolism probes, neurotransmitter and neuroreceptor probes and neuropathological marker probes are introduced in this review. Key words: Alzheimer′s disease; Positron-emission tomography; Molecular probes; Trends