Abstract
Gastric resection can cause a multifactorial clinical manifestations of dyspepsia, such as flatulence, diarrhea, weight loss, and fat diarrhea. Exocrine pancreatic insufficiency (EPI) is one of the possible mechanisms of fat maldigestion following gastric surgery, the main causes may be related to rapid gastric emptying; asynchrony between gastric emptying and bilio-pancreatic secretion due to new tracts of various reconstructions; bacterial overgrowth after gastrectomy and so on. Oral pancreatic enzyme replacement therapy (PERT) is the mainstay of treatment for EPI, due to lack of available evidence so far, the efficacy and safety of pancreatic enzyme substitution in patients following gastric resection remains unclear and cannot be generally recommended. This review will sum up the revelant studies addressing EPI and PERT after gastric resection in recent years, and summarizes the mechanisms, clinical diagnostic methods and PERT treatment perscription of EPI after gastrectomy to improve the cognition of clinicans. Key words: Gastrectomy; Exocrine pancreatic insufficiency; Dyspepsia; Pancreatic enzyme replacement therapy
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
