Research progress of NPR genes in signal pathway of salicylic acid mediated plant disease resistance

Pan Wang,Meiqin Xiang,T Coenye,H Huang

doi:10.1051/e3sconf/202014501038

Abstract

Salicylic acid (SA) is considered to be an endogenous signal molecule in plants, and it is related to many resistances in plants. In Arabidopsis, Non-expressor of pathogenesis-related gene1 (NPR1) mediates the expression of pathogenesis-related genes (PRs) and systemic acquired resistance (SAR) induced by SA. NPR1 is a key factor in SA signaling pathway, and the research shows that NPR1, NPR3 and NPR4 play a key role in SA mediated plant disease resistance. In this review, the interaction between NPR and transcription factors is discussed, and we also describe the progress of NPR in SA mediated SAR signal transduction pathway, likewise, we introduce the relationship between NPR1 and its paralogues NPR3/NPR4. This paper analyzes the research prospect of NPR as the intersection of multiple signal paths.

Highlights

Plants are usually infected by a variety of pathogens in the process of growth and development
3 Conclusion In Arabidopsis, rice[16], apple[19], tomato[31], wheat[32] and many other plants, it has been found that overexpression of Non-expressor of pathogenesis-related gene1 (NPR1) gene can improve plant disease resistance
According to the types of plant resistance, the mechanism of NPR1 in plant resistance can be divided into the following three situations. the first belongs to basic resistance: in uninfected plant cells, the closed conformation of inactive NPR1 is mediated by direct interaction between BTB / POZ and trans activated (TA) domain

Summary

Introduction

Plants are usually infected by a variety of pathogens in the process of growth and development. After ETI is activated by R-gene, the resistance produced by plants has a typical form, the infected site can prevent the spread of pathogens in the way of rapid necrosis of local tissues, which is called hypersensitivity response (HR)[5], and trigger the corresponding SAR[6]. When the plant is infected by pathogenic bacteria, the accumulation of SA in the plant induces the monomer of NPR1 by destroying the disulfide bond between cysteine through Trxs, and causes the change of redox state in the cell, affecting the NPR1 signaling pathway[20].The research shows that there are five amino acid sequences similar to NPR1 in Arabidopsis gene tissue, which are named npr, npr, npr npr and npr, in addition, the research of the function of npr showed that the gene was resistant to Pseudomonas syringae and Erysiphe cichoracearum[21]. Effectors may affect the transcription level of NPR1 by targeting various transcription factors that regulate NPR1 expression[27]

The mechanism of NPR in plant disease resistance

NPR1 as a key regulator of SA signaling

Conclusion

Future considerations