Abstract

Natural killer T(NKT)cells are a unique subset of lymphocytes, which express both T and natural killer(NK) cell surface markers as well as functional characteristics.They connect innate and acquired immunity, restrictedly recognize glycolipid antigens presented by CD1d molecule and influence the balance between T helper cell type 1 (Th1)and Th2 by regulating the secretion of cytokines. Natural killer T cells participate in the immune regulation generally. Focus on recent years found that natural killer T cells played important roles in Th1/Th2 imbalance and airway hyper responsiveness (AHR) of asthma.This paper reviewed the progress of the characteristics of natural killer T cells and the association with bronchial asthma. Key words: natural killer T (NKT )cell; bronchial asthma; immune balance

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