Research progress of local sustained-release drug delivery system in the treatment of peri-implantitis

Abstract

With the increasing demand for oral implants, the incidence of peri-implantitis is also increasing year by year, and serious cases may even lead to implant loss. Studies have shown that the clinical treatment of peri-implantitis is divided into resection and regenerative surgery, and conventional drug treatment is divided into systemic and local administration. Compared with systemic administration, the local sustained-release system can not only reduce the adverse reactions and drug resistance of systemic administration, but also achieve a high concentration of drugs that can continuously kill bacteria in the periodontal pocket. Therefore, the treatment of peri-implantitis with local sustained-release system has become a research hotspot at home and abroad. This article reviews the research progress of local sustained-release system in the treatment of peri-implantitis in recent years.