Research progress of injectable bone tissue engineering scaffold material

Abstract

Injectable bone tissue engineering scaffold material has a certain form and mechanical strength. It can be loaded with seed cells for injection to the defected site of bone tissue in the form of fluid. After that, structural recovery and functional reconstruction are achieved, and the new bone is formed ultimately. This material has the characteristics of small trauma and good plasticity. It can repair the irregular bone defects and well associate with growth factor, which is the ideal method for repairing bone tissue defects up to now. Among the various injectable bone tissue engineering materials, bioceramic materials, polymer materials, etc. have been proved to have a high biological compatibility and good mechanical properties. That makes these materials become the focus of current research in bone tissue engineering materials. In this paper, the development and application of bioceramic materials, polymer materials, bioceramics and polymer composites were reviewed. Key words: Bone tissue engineering; Scaffold materials; Biomaterial