Research progress of cannabidiol in the treatment of epilepsy

Abstract

In the treatment of refractory epilepsy, especially in Dravet syndrome and Lennox-Gastaut syndrome, cannabidiol, an anticonvulsant component of marijuana, has shown significant efficacy and safety. However, its mechanism of action and interaction with other drugs are still unclear. For refractory patients who have been treated with a variety of antiepileptic drugs, cannabidiol makes their treatment more promising but also more complicated. This review focuses on the mechanism of cannabidiol and its clinical research progress in the treatment of refractory epilepsy. Key words: Epilepsy; Marijuana; Cannabidiol; Antiepileptic drugs