Abstract

Aplastic Anemia (AA) is an autoimmune disease mainly mediated by T cells. On the one hand, focusing on the current research status of different T lymphocytes in AA. On the other hand, because a variety of cytokines are involved in the occurrence, development and outcome of AA, the research progress of multiple cytokines (interleukin, interferon and tumor necrosis factor) in the pathogenesis of AA was analyzed at the same time. Facing the current status of recurrence and ineffective IST treatment in clinical treatment, we explore the role of mesenchymal stem cells from different tissues in immunity, and explore their potential therapeutic advantages may bring new ideas for clinical treatment. Exploring the pathogenesis of AA in multiple dimensions will bring about treatment ideas that will also be multi-dimensional.

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