Abstract

Tumor vaccines include peptide or protein vaccine, tumor cell vaccine, anti-idiotype vaccine, dendritic cell vaccine, DNA vaccine and viral-vector based vaccine. The recombinant protein vaccine is prepared by the recombination, construction, and expression of target antigen gene. With the development of recombination, expression and purification technologies, recombinant protein vaccine provides a research and development method for tumor immunotherapy study. This article reviews on the recombinant protein vaccine of tumor antigen. Key words: Cancer vaccines; Recombinant proteins; Antigens, neoplasm

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