Abstract

IgG4-related diseases (IgG4-RD) is a group of diseases characterized by abnormally elevated levels of IgG4 antibodies and infiltration of IgG4+ plasma cells. Currently, Western medicine mainly uses hormones, immunosuppressants, and biologically targeted therapies for treatment. Traditional Chinese medicine mainly uses dialectic therapy to treat the disease. The syndrome types are mostly Yin deficiency of the liver and kidney, phlegm and blood stasis, Yang deficiency of the spleen and kidney, and damp-heat of the liver and gallbladder. This article provides a review of the research progress in epidemiology, clinical manifestations, diagnosis, and treatment of IgG4-related diseases in Chinese and Western medicine.

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