Research progress in the pathogenesis and treatment of diabetic nephropathy

Abstract

Diabetic nephropathy (DN) is one of the most common, frequent, age-related diseases, and it is also an important cause of chronic renal failure and end-stage renal diseases. It has always been one of the research hotspots. The high cost of treatment will bring a great burden to society and families. Therefore, it is very important to study the pathogenesis and treatment methods of DN. At present, many methods have been put forward for clinical diagnosis and treatment like Thiazolidinediones, renin inhibitor drug -aliskiren, tregs cells. These methods have their own advantages and disadvantages. However, the etiology of diabetic nephropathy is complicated and the course of the disease is long, and current treatments cannot achieve the expected target. Scholars also have studied many symptomatic treatment methods for different pathogenesis. However, the specific pathogenesis of DN has not yet been fully elucidated, and there is no special medicine for DN yet. This article briefly reviews the pathogenesis and treatments of DN based on the existing kinds of literature and new advances to provide some references for its clinical diagnosis and treatment.