Abstract
Ultraviolet A and blue lights in riboflavin cross-linking are effective approaches to increase the mechanical and biochemical rigidity of collagen fibers. The effect of cross-linking and the safety of the eye are affected by riboflavin, which acts as a photosensitizer and protective agent. The riboflavin content in the cornea and sclera relates to many factors and needs to be detected by reasonable methods. This article focuses on the two methods mentioned above. Key words: Riboflavin; Permeability; Cornea; Sclera; Collagen cross-linking
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