Abstract
Myocardial fibrosis is a pathological process characterized by fibroblast proliferation and collagen deposition, which occurs in the normal structure of the myocardium. MicroRNAs (miRNAs) are a class of endogenous, non-coding RNA of approximately 22 nucleotides in length, regulating gene expression at post-transcriptional level by complementary pairing with the target gene mRNA. Recent studies have showed that miRNAs play an important role in the formation of myocardial fibrosis, therefore, much attention has been paid to miRNAs as they may serve as targets for prevention and treatment of myocardial fibrosis. Key words: Myocardial fibrosis; MicroRNAs; Gene regulation
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