Abstract
Acute kidney injury (AKI) is a common clinical critical illness. Several foreign studies showed that patients with drug-induced AKI accounted for 15%-27% of patients with AKI occurred during hospitalization and a domestic research showed that the proportion was 28.9%. The evaluation methods of causality assessment between drugs and AKI are experts judgement or global introspection, Karch & Lasagnar evaluation method, recommended standard for ADR monitoring center of Health Planning Commission of China, and Naranjo Adverse Drug Reaction Probability Scale(NADRPS), etc. The etiology of drug-induced AKI can be divided into 3 categories, including prerenal, renal, and postrenal. Predisposing factors include advanced age, diabetes, hypertension, chronic kidney disease, low serum albumin, etc. Prevention measures are avoiding and correcting all kinds of risk factors, selecting drugs of low toxicity or no toxicity to kidney, and if necessary early dialysis treatment should be given. Development and improvement of computer aided automatic alert system is very important in prevention, early diagnosis and early treatment of AKI. Key words: Inpatients; Acute kidney injury; Automated alert system
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