Research progress and preventive strategy of HPV and cervical cancer and other related cancers

Abstract

This paper comprehensively reviews the research on the relationship between HPV and cervical cancer and other cancers and expounds the pathogenesis of cancer caused by HPV and its negative impact on the body. The screening methods and their effectiveness are reviewed, and the relevant research and latest developments of vaccines are summarized. First, the basic knowledge about HPV (including the structure and typing of the virus and the mechanism of infection of the virus) is introduced, and the screening method and its effectiveness are explored. Furthermore, the relationship between cervical cancer and HPV infection (including the mechanism of occurrence, the type of virus that causes cervical cancer, and the characteristics after infection) is discussed emphatically. Subsequently, the relationship between HPV infection and other cancers (including the mechanism of infection, classification and post-infection characteristics) was further explored, such as oral cancer, anal cancer, and reproductive organ cancer (except cervical cancer that has been introduced above). In the end, the current research results on HPV prevention and the challenges to be met from the current point of view are summarized, and the outlook and some suggestions for the research direction of future vaccines are made.