Abstract
Abstract Background: In order to identify research priorities for aortic disease, a partnership between the Vascular Society of Great Britain and Ireland (VSGBI) and the James Lind Alliance (JLA) was established to capture the interests of a wide group of patients, carers and health professionals. One of the aims of the partnership was to establish the top 10 research priorities in the field of aortic disease. Methods: A modified JLA Priority Setting Partnership was undertaken, during which healthcare professionals, patients and carers participated independently in two Vascular Society of Great Britain and Ireland (VSGBI)-led Delphi processes identifying research priorities in aortic disease. An aortic Special Interest Group composed of patients and healthcare professionals assessed the two lists of priorities, amalgamating similar priorities and generating a final list for ranking. An offer was sent to various patients, carers and healthcare professionals from different backgrounds with an interest in aortic disease to attend the final consensus workshop where a ranked top 10 list of aortic disease research priorities was produced using a nominal group technique. Results: A total of 1,231 research priorities relating to general vascular surgery were submitted by 481 clinicians. From these, 162 aortic-specific research priorities were identified and combined into 15 final clinical priorities. In addition, 582 research priorities related to vascular surgery in general were submitted by 373 patients or carers. From these, 24 further aortic-specific research priorities were identified after combining similar priorities. Amalgamation of the clinician and patient priorities resulted in 18 priorities that were taken to the final consensus workshop, where a ranked top 10 list of aortic disease research priorities was produced. These priorities include themes of diagnosis, surveillance, management, recovery and predisposition. Conclusion: A collaborative effort between healthcare professionals and patients has identified a ranked top 10 list of aortic disease research priorities. This list will inform and guide clinicians, researchers and funders for the foreseeable future and will support future research that encompasses the important interests and representation of the wider network involved and affected by aortic disease.
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