Abstract
In this paper, the method using lensless microscopic imaging techniques, to reconstruct the three-dimensional morphology of tumor cells is given. We demonstrate lensless microscopic platform which only use a CMOS image sensor and a controllable color LED array. Based on the principle of lensless computational imaging, we use the phase recovery algorithm under multi-wavelength and the diffraction tomography algorithm under multi-angle illumination, to reconstruct the three-dimensional morphology of tumor cells. Experiments have verified that this method can achieve large field of view imaging without labeling and reconstruct the three-dimensional morphology of tumor cells, which provides reliable morphological parameters for clinical research and is of great significance to the development of portable medical care.
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