Research on the medication rules of the famous Chinese medicine professor Ma Zhanping in the treatment of COPD by data mining

Abstract

Objective: To collect and organize the clinical TCM prescriptions of Professor Ma Zhanping in the diagnosis and treatment of chronic obstructive pulmonary disease (COPD), to clarify and analyze the commonly used TCM compatibility of Professor Ma Zhanping in the treatment of COPD, and to summarize his clinical experience in the treatment of COPD. In order to provide some reference for clinical treatment of COPD. Methods: The Chinese medicine prescriptions for COPD treated by Professor Ma Zhanping in the outpatient department of Shaanxi Provincial Hospital of Traditional Chinese Medicine from January 2019 to March 2021 were collected. After screening, data mining techniques such as statistical frequency, association rule analysis, drug network link relationship analysis, and cluster analysis were used, analyze the drug compatibility relationship, summarize the medication rules, and visualize the results. Results: A total of 271 first-diagnostic prescriptions were screened, involving 160 flavors of drugs, and the frequency of use reached 4012 times. Among them, commonly used drugs include bitter almond, ephedra, coix seed, pinellia chinensis and perilla seed. Coix seed, at the same time cluster analysis obtained 4 groups of clusters. Conclusion: Professor Ma Zhanping believes that the treatment of COPD should firstly identify the external and internal injuries, differentiate the syndrome by stages, and choose the prescription flexibly, so as to promote the normalization of qi in the body, and then the qi will be smooth and smooth.