Research on the influencing factors of periprostatic nerve block anaesthesia

Abstract

Objective To investigate the influence factors of periprostatic nerve block(PNB) anaesthesia. Methods A total of 375 patients who underwent prostate biopsy under PNB were analyzed retrospectively from July 2014 to February 2018. It was evaluated the correlation of the anesthetic efficacy of PNB with age, prostate volume, PSA, body mass index, spouse, degree of education, occupation, diabetes history, operation time, number of cores and clinical stage. A visual analog scale (VAS) were used to assess pain of the patients. Univariate analysis was performed for each factor. Factors found to be significantly different that were further analyzed using multiple linear regression analysis. Results The average VAS score of all patients was 2.5±1.4. Univariate analysis showed that the following factors were associated with the anesthetic efficacy of PNB: age (F=2.262, P=0.029), prostate volume (F=2.529, P=0.011), occupation (F=2.203, P=0.042), operation time (F=2.233, P=0.033), number of cores (F=2.401, P=0.016) and diabetes history (F=2.271, P=0.027). Multiple linear regression analysis showed that prostate volume (t=3.742, P<0.001), number of cores (t=4.252, P<0.001) and diabetes history (t=-2.242, P=0.032) were independent factors. The VAS score of patients with large volume prostate was higher than that of small volume prostate. The number of cores was high, and the VAS score was higher. However, diabetic patients had lower VAS score. Conclusions The anesthetic efficacy of PNB was poor in patients with larger prostate volume and more number of cores. However, patients with chronic diabetes had better pain tolerance. Key words: Periprostatic nerve block anaesthesia; Pain; Influencing factors