Abstract

The inertial focusing effect of particles in microchannels shows application potential in engineering practice. In order to study the mechanism of inertial migration of particles with different scales, the motion and distribution of two particles in Poiseuille flow are studied by the lattice Boltzmann method. The effects of particle size ratio, Reynolds number, and blocking rate on particle inertial migration are analyzed. The results show that, at a high blocking rate, after the same scale particles are released at the same height of the channel, the spacing between the two particles increases monotonically, and the change in the initial spacing has little effect on the final spacing of inertial migration. For two different size particles, when the smaller particle is downstream, the particle spacing will always increase and cannot remain stable. When the larger particle is downstream, the particle spacing increases firstly and then decreases, and finally tends to be stable.

Highlights

  • Research on the Inertial MigrationThe precise focusing process of particles is a critical step of separation and screening techniques [1,2,3] and is widely used in the fields of biochemical engineering and medical areas

  • Segré and Siberberg [5] proposed that the particles migrated by inertia to the equilibrium position of the cross section, and ordered longitudinally along the main flow direction to form particle trains that may result from particle–particle interactions

  • The results show that, in the case of a high blocking ratio, the final particle spacing of two particles of equal diameter released at the same height does not change with the change in the initial spacing of the particles

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Summary

Introduction

Research on the Inertial MigrationThe precise focusing process of particles is a critical step of separation and screening techniques [1,2,3] and is widely used in the fields of biochemical engineering and medical areas. The suspended particles naturally gathered together and migrated to the equilibrium position, under specific flow fields and geometric conditions, confirming, by Segré and Siberberg [5] with extensive experiments, that the particles gathered into a concentric ring on the cross section of the channel and continued to move in the flow direction. This focusing was thought to be a balance of shear-induced, wall-induced, and rotation-induced lift forces, and the underlying mechanisms have been extensively investigated [6]. Segré and Siberberg [5] proposed that the particles migrated by inertia to the equilibrium position of the cross section, and ordered longitudinally along the main flow direction to form particle trains that may result from particle–particle interactions

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